Leucovorin for autism: Why physicians must protect hope from hype

In September 2025, The Atlantic reported on a frenzy surrounding leucovorin, a folate derivative long used in oncology and rheumatology. Families desperate for answers were suddenly told it might be a miracle therapy for autism. Waitlists stretched years, clinics were overwhelmed, and hope surged. The problem was not just scientific, it was political. When President

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Leucovorin for autism: Why physicians must protect hope from hype originally appeared in KevinMD.com.

 

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